Bart C Jacobs Selected Research

Guillain-Barre Syndrome

1/2022	Novel approach to monitor intravenous immunoglobulin pharmacokinetics in humans using polymorphic determinants in IgG1 constant domains.
1/2022	Population Pharmacokinetic Modelling of Intravenous Immunoglobulin Treatment in Patients with Guillain-Barré Syndrome.
1/2022	Association of mannose-binding lectin 2 gene polymorphisms with Guillain-Barré syndrome.
10/2021	Intravenous immunoglobulin treatment for mild Guillain-Barré syndrome: an international observational study.
1/2021	Changes in motor nerve excitability in acute phase Guillain-Barré syndrome.
1/2021	Guillain-Barré syndrome during the Zika virus outbreak in Northeast Brazil: An observational cohort study.
1/2021	Second intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis (SID-GBS): a double-blind, randomised, placebo-controlled trial.
1/2021	COVID-19 vaccine and Guillain-Barré syndrome: let's not leap to associations.
1/2021	Antiglycolipid antibodies in Guillain-Barré and Fisher syndromes: discovery, current status and future perspective.
11/2020	Chemoenzymatic Synthesis of Campylobacter jejuni Lipo-oligosaccharide Core Domains to Examine Guillain-Barré Syndrome Serum Antibody Specificities.

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Bart C Jacobs Research Topics

Disease

60	Guillain-Barre Syndrome 01/2022 - 04/2002
19	Infections 01/2022 - 02/2004
12	Polyneuropathies (Polyneuropathy) 01/2021 - 12/2004
8	Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) 01/2021 - 06/2011
7	Miller Fisher Syndrome (Fisher Syndrome) 01/2019 - 04/2002
5	Paraproteinemias (Monoclonal Gammopathy) 12/2018 - 06/2006
5	Respiratory Insufficiency (Respiratory Failure) 03/2018 - 06/2010
5	Disease Progression 01/2018 - 02/2008
3	Pain (Aches) 10/2021 - 10/2007
3	Muscle Weakness 01/2021 - 06/2009
3	Autoimmune Diseases (Autoimmune Disease) 03/2014 - 02/2004
3	Diarrhea 03/2011 - 02/2008
3	Ophthalmoplegia (External Ophthalmoplegia) 01/2009 - 04/2002
2	Arbovirus Infections 12/2021 - 01/2021
2	Sudden Infant Death (SID) 01/2021 - 12/2018
2	Human Influenza (Influenza) 12/2019 - 01/2014
2	Encephalitis (Encephalitis, Rasmussen) 01/2019 - 12/2015
2	Immune System Diseases (Immune Disorders) 12/2018 - 06/2009
2	Sepsis (Septicemia) 01/2018 - 01/2017
2	Venous Thrombosis (Deep-Vein Thrombosis) 01/2018 - 01/2017
2	Peripheral Nervous System Diseases (PNS Diseases) 03/2014 - 11/2009
1	Central Nervous System Diseases (CNS Diseases) 01/2021
1	Zika Virus Infection 01/2021
1	Dengue (Dengue Fever) 10/2020
1	Nervous System Diseases (Neurological Disorders) 01/2019
1	Paraneoplastic Syndromes (Paraneoplastic Syndrome) 12/2018
1	Hypoalbuminemia 02/2017
1	Inflammation (Inflammations) 02/2017
1	Chronic Hepatitis (Chronic Active Hepatitis) 01/2017
1	Vasculitis (Vasculitides) 04/2015
1	Granulomatosis with Polyangiitis (Wegener's Granulomatosis) 04/2015
1	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 03/2015
1	Gastroenteritis 12/2013
1	Demyelinating Diseases (Demyelinating Disease) 01/2013
1	Ventilator-Associated Pneumonia 08/2011
1	Brachial Plexus Neuritis (Parsonage Turner Syndrome) 06/2011
1	Fatigue 03/2011
1	Polyradiculoneuropathy (Polyradiculoneuritis) 01/2011
1	Reactive Arthritis (Reiter Disease) 10/2009
1	Enteritis 10/2009
1	Dysarthria (Spastic Dysarthria) 01/2009
1	Ataxia (Dyssynergia) 01/2009
1	Paralysis (Palsy) 05/2008

Drug/Important Bio-Agent (IBA)

42	AntibodiesIBA 01/2022 - 04/2002
26	GangliosidesIBA 01/2022 - 04/2003
23	Intravenous Immunoglobulins (IVIG)FDA Link 01/2022 - 10/2003
15	Immunoglobulin G (IgG)IBA 01/2022 - 05/2005
9	Immunoglobulin M (IgM)IBA 10/2020 - 12/2005
7	Biomarkers (Surrogate Marker)IBA 01/2021 - 11/2009
6	GlycolipidsIBA 12/2021 - 12/2008
5	OligosaccharidesIBA 11/2020 - 12/2004
4	galactocerebrosideIBA 12/2019 - 01/2018
4	AutoantibodiesIBA 12/2016 - 01/2009
4	lipid-linked oligosaccharidesIBA 12/2013 - 07/2007
3	G(M1) GangliosideIBA 01/2022 - 12/2011
3	Amantadine (Aman)FDA LinkGeneric 01/2021 - 03/2011
3	Biological ProductsIBA 01/2019 - 08/2016
3	AntigensIBA 08/2014 - 04/2003
2	Methylprednisolone FDA LinkGeneric 01/2022 - 10/2007
2	IV(4)-galactosyl-N-acetylganglioside GD1aIBA 01/2021 - 12/2019
2	AlbuminsIBA 02/2017 - 01/2017
2	Antiviral Agents (Antivirals)IBA 01/2017 - 01/2017
2	Immunoglobulins (Immunoglobulin)IBA 04/2015 - 03/2014
1	Mannose (D-Mannose)IBA 01/2022
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021
1	Proteins (Proteins, Gene)FDA Link 01/2021
1	COVID-19 VaccinesIBA 01/2021
1	Viral RNAIBA 10/2020
1	Alemtuzumab (Campath)FDA Link 01/2020
1	A 17 (A-17)IBA 12/2019
1	Serum AlbuminIBA 02/2017
1	InterferonsIBA 01/2017
1	Ribavirin (Virazole)FDA LinkGeneric 01/2017
1	neonatal Fc receptorIBA 01/2016
1	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 04/2015
1	Myeloblastin (Proteinase 3)IBA 04/2015
1	CytokinesIBA 04/2015
1	Myelin-Associated GlycoproteinIBA 07/2014
1	VaccinesIBA 01/2014
1	Sialic Acid Binding Ig-like Lectin 1IBA 06/2013
1	CarbohydratesIBA 07/2011
1	Indicators and Reagents (Reagents)IBA 06/2010
1	Genetic Markers (Genetic Marker)IBA 10/2009
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 06/2009
1	GlucocorticoidsIBA 06/2009
1	GQ1b gangliosideIBA 01/2009
1	EpitopesIBA 12/2008

Therapy/Procedure

8	Artificial Respiration (Mechanical Ventilation) 01/2021 - 06/2010
4	Plasma Exchange 01/2021 - 03/2011
3	Aftercare (After-Treatment) 02/2017 - 03/2014
2	Critical Care (Surgical Intensive Care) 10/2020 - 01/2011
2	Therapeutics 01/2020 - 06/2011
2	Central Venous Catheters 01/2018 - 01/2017
1	Length of Stay 10/2020
1	Immunotherapy 01/2019
1	Tracheostomy 01/2017
1	Catheters 01/2017
1	Mechanical Ventilators (Ventilator) 08/2011
1	Intravenous Injections 05/2008
1	Intraperitoneal Injections 05/2008